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384959

Postnatal Development of the Rabbit Cerebellum

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

Physiology

Abstract

The purpose of the current study was to provide an overview of the rabbit 
cerebellum's postnatal developmental stages. Forty rabbit cerebella of postnatal 
ages (PN1, PN 5, PN8, PN15, PN22, 1M, 2M, 3M, 4M, 5M and 6M) were obtained 
from the Balady rabbits. In, PN1 the cerebellar cortex consisted of four layers: an 
external granular layer (EGL), a molecular layer, a Purkinje cell layer, and an 
internal granular layer. The thickness of the EGL reached its maximum, consisted 
of five to six layers of oval or spherical cells. The Purkinje cell layer retained 
immature. Purkinje cells had vesicular nuclei, prominent nucleoli, and an 
amphiphilic cytoplasm were arranged in two or three different layers. At PN 5, 
EGL decreased in thickness while Purkinje neurons were arranged in a well
developed single row. Myelination of the white matter appeared more evident. 
At later postnatal ages, the EGL was decreased in thickness until disappeared, 
while internal granular layer and molecular layer increased in thickness until the 
anatomical characteristics of the mature cerebellum were reached from two 
months onward. Cerebellum was important for motor coordination; muscle 
tones and maintaining the equilibrium of the body. An extended process that 
takes place during postnatal life gives the mature cerebellum its ultimate 
structure.  

DOI

10.21608/jcvr.2024.384959

Keywords

histology, Cerebellum, postnatal development, Rabbits, Histogenesis

Authors

First Name

Hanaa

Last Name

Elnagar

MiddleName

Y.

Affiliation

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Email

-

City

-

Orcid

-

First Name

S.

Last Name

Emara

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Nada

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Nazema

Last Name

Abdel-Megeid

MiddleName

S.

Affiliation

-

Email

-

City

-

Orcid

-

Volume

6

Article Issue

2

Related Issue

50875

Issue Date

2024-10-01

Receive Date

2024-10-08

Publish Date

2024-10-01

Page Start

249

Page End

278

Print ISSN

2636-4018

Online ISSN

2636-4026

Link

https://jcvr.journals.ekb.eg/article_384959.html

Detail API

https://jcvr.journals.ekb.eg/service?article_code=384959

Order

384,959

Type

Original Article

Type Code

799

Publication Type

Journal

Publication Title

Journal of Current Veterinary Research

Publication Link

https://jcvr.journals.ekb.eg/

MainTitle

Postnatal Development of the Rabbit Cerebellum

Details

Type

Article

Created At

24 Dec 2024