A total of thirty native draft horses were divided into two main groups; Group 1: had 
fifteen healthy, Group 2: had fifteen horses suffered from sand colic. All horses were 
undergone to a full clinical investigation. DRAMISKI 4 vet diagnostic ultrasound device was 
used. Horses with sand colic showed mild to moderate colic, anorexia, chronic weight loss, 
poor performance, sandy manure and characteristic pouring sand sound that heard in 
ventral abdomen in the area just caudal to the xiphoid region. The rectal palpation in 
horses with sand colic revealed increased hardness of fecal ball and gassy dilation or 
impacted segment the colon. The wall of the large colon was seemed "brighter" and more 
hyperechoic by ultrasonography. The hematobiochemical findings revealed that the values 
of RBCs, Hb, monocytes, sodium, chloride, potassium and calcium were significantly 
decreased, while PCV, WBCs, neutrophils and lactate dehydrogenase were significantly 
increased in horses with sand colic compared to healthy ones.