Neospora caninum was thought to be the parasitic agent causing bovine abortion and newborn mortality in Norway's dogs as well as other countries. Cyst-producing protozoan parasite; Neospora caninum, that have two reproductive stages during its life cycle include asexual stage occurs in a broad intermediate host range includes  (cattle, buffalo, sheep and goat) and a sexual stage which occurs in different Canids species is the cause of the disease. It is transferred from the definitive host to the intermediate hosts directly by direct contact with dogs or indirectly through contamination of their feed by dogfeces. Other animals may share in the complete life cycle like birds and rodents. In farm animal, it can spread vertically via transplacental transfer from the dam to the fetus or horizontally by consumption of oocysts that the hosts disseminated with their feces. It causes storm of abortions, stillbirths, infertility, and loss of milk production, which lead to great economic losses. In addition, the Neospora caninum antibodies in dogs were detected all over the world. Additionaly Neospora caninumis a possible cause of canine neuromuscular paralysis. N. caninum in seropositive animals could be detected by numerous techniques including, indirect fluorescent antibody technique, enzyme-linked immunosorbent assay (ELISA), the direct agglutination technique and immunoblotting. Many restrictions are undergone to control neosporosis wide distribution among animals and consequently its economic loses. It has been concluded that the main methods useful for control of Neospora caninum include good farm biosecurity, therapy and vaccination. The current review focused on a broad overview of Neospora caninum in farm animals.