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341339

Neurally Adjusted Ventilatory Assist versus Pressure Support Ventilation during weaning A meta-analysis of randomized trials

Article

Last updated: 24 Dec 2024

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Abstract

Background: Prolonged ventilatory support is associated with poor clinical outcomes. pressure support ventilation modes , are frequently used in clinical practice but are associated with patient–ventilator asynchrony and deliver fixed levels of assist. Neurally adjusted ventilatory assist (NAVA), a mode of partial ventilatory assist that reduces patient–ventilator asynchrony compared with other partial support modes for patients with difficult weaning Objectives:conduct a meta-analysis comparing neurally adjusted ventilatory assist (NAVA) with pressure support ventilation (PSV) in adult ventilated patients &clinical outcomes. Study design: Meta-analysis was used to address this concern. Sittings: Meta-analysis-based study following the PRISMA (Preferred Reporting Items for Systematic Reviews and MetaAnalyses) guidelines. Methods: Online databases (PubMed, Embase, BioMed, and the Cochrane Central Register of Controlled trials) were used for randomized studies ever performed in humans with NAVA & PSV in any clinical setting. Results: 12 studies (n = 799 patients) were included. Regarding the primary outcome, patients weaned with NAVA had a higher success rate compared with pressure support ventilation For the secondary outcomes, NAVA may reduce duration of mechanical ventilation and hospital mortality and prolongs ventilator-free days when compared with other modes. Conclusion: Our study suggests that the NAVA mode may improve the rate of weaning success compared with pressure support ventilation for difficult weaning

DOI

10.21608/bmfj.2024.216982.1839

Keywords

Mechanical Ventilation, Neurally adjusted ventilatory assist (NAVA), pressure support ventilation (PSV), patient-ventilator interaction

Authors

First Name

Enas

Last Name

Mahdy

MiddleName

Wageih

Affiliation

Assistant Professor of Anesthesia & Intensive Care Faculty of Medicine - Benha University

Email

ewm01221592827@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Abd El-Hamid

MiddleName

Mostafa

Affiliation

Department of anesthesia & intensive care, Faculty of Medicine, Benha University

Email

ahmedmostafa@fmed.bu.edu.eg

City

-

Orcid

-

First Name

Esraa

Last Name

Mohamed Abdalla

MiddleName

salah

Affiliation

Department of Critical Care Medicine, Faculty of Medicine, Benha University

Email

esraasalah2612@gmail.com

City

-

Orcid

-

First Name

Asmaa

Last Name

Mohammed Ebaed

MiddleName

Bahy

Affiliation

Departemnt of Critical Care Medicine, Faculty of Medicine, Benha University

Email

asmaa.bahy8819@gmail.com

City

-

Orcid

-

Volume

41

Article Issue

2

Related Issue

47522

Issue Date

2024-05-01

Receive Date

2023-06-11

Publish Date

2024-05-01

Page Start

191

Page End

204

Print ISSN

1110-208X

Online ISSN

2357-0016

Link

https://bmfj.journals.ekb.eg/article_341339.html

Detail API

https://bmfj.journals.ekb.eg/service?article_code=341339

Order

526

Type

Review Article

Type Code

920

Publication Type

Journal

Publication Title

Benha Medical Journal

Publication Link

https://bmfj.journals.ekb.eg/

MainTitle

Neurally Adjusted Ventilatory Assist versus Pressure Support Ventilation during weaning A meta-analysis of randomized trials

Details

Type

Article

Created At

24 Dec 2024