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327051

Study on the Impact of metabolic associated fatty liver disease (MAFLD) on patients with Corona Virus Disease – 2019 (COVID-19)

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Last updated: 04 Jan 2025

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Abstract

Purpose: This study aimed to assess the impact of metabolic (dysfunction) associated fatty liver disease (MAFLD) on the outcome of patients with COVID-19.
Patients and Methods: This prospective observational study assessed the impact of MAFLD on COVID-19 outcomes in patients treated at Toukh Fever Hospital from January 2022 to February 2023. The study involved adult patients with confirmed COVID-19, excluding those with specific liver-related conditions, and included comprehensive clinical, laboratory, and ultrasonographic assessments. The severity of COVID-19 was evaluated according to the Egyptian protocol, and the diagnosis of MAFLD followed international consensus criteria.
Results: Patients with MAFLD had a higher BMI, a greater prevalence of hypertension and type 2 diabetes, and exhibited unique laboratory findings, including lower hemoglobin and lymphocyte counts, elevated inflammatory markers, and dyslipidemia. The severity of COVID-19 and mortality rates were significantly elevated in patients with MAFLD.
Conclusion: Patients with MAFLD exhibited distinct clinical and laboratory features and were at risk of developing severe COVID-19 and worse outcomes.

DOI

10.21608/bmfj.2023.242125.1924

Keywords

COVID-19, metabolic associated fatty liver disease (MAFLD), Outcome

Authors

First Name

Mahmoud

Last Name

Oraby

MiddleName

-

Affiliation

Hepatology, Gastroenterology and Infectious Diseases Department, Toukh Fever Hospital, Qalyubia Directorate of Health, Ministry of Health and Population, Egypt

Email

moraby@yahoo.com

City

-

Orcid

-

First Name

Mahmoud

Last Name

Mazoun

MiddleName

-

Affiliation

Hepatology, Gastroenterology and Infectious Diseases Department, Toukh Fever Hospital, Qalyubia Directorate of Health, Ministry of Health and Population, Egypt

Email

mahmoudmazoun84@gmail.com

City

-

Orcid

-

First Name

Ahmed Qassem

Last Name

Mohamed

MiddleName

-

Affiliation

Department of Hepatogastroentrology and Infectious Diseases, Al-Azhar University, Egypt

Email

ahmedqassem@gmail.com

City

-

Orcid

-

First Name

Mai

Last Name

Fawzy

MiddleName

-

Affiliation

Radiology Department, Benha Fever Hospital, Qalyubia Directorate of Health, Ministry of Health and Population, Egypt

Email

maifawzy2007@yahoo.com

City

-

Orcid

-

First Name

Taher

Last Name

Abdel-Aziz

MiddleName

-

Affiliation

Clinical Research Unit, Directorate of Health Affairs in Qalyubia, Ministry of Health and Population, Egypt

Email

taheralnomany@yahoo.com

City

-

Orcid

-

First Name

Ismail

Last Name

Dahshan

MiddleName

-

Affiliation

Department of Family Medicine, Faculty of Medicine, Sues Canal University, Egypt

Email

dahshan1663@hotmail.com

City

-

Orcid

-

Volume

40

Article Issue

3

Related Issue

44745

Issue Date

2023-12-01

Receive Date

2023-10-12

Publish Date

2023-12-01

Page Start

817

Page End

827

Print ISSN

1110-208X

Online ISSN

2357-0016

Article File

BMFJ_Volume 40_Issue 3_Pages 817-827.pdf

PDF . 745.5kB

Link

https://bmfj.journals.ekb.eg/article_327051.html

Detail API

https://bmfj.journals.ekb.eg/service?article_code=327051

Order

20

Type

Original Article

Type Code

787

Publication Type

Journal

Publication Title

Benha Medical Journal

Publication Link

https://bmfj.journals.ekb.eg/

MainTitle

Study on the Impact of metabolic associated fatty liver disease (MAFLD) on patients with Corona Virus Disease – 2019 (COVID-19)

Details

Type

Article

Created At

24 Dec 2024