Beta
315817

Estimated Glomerular Filtration Rate and Microalbuminuria as Biomarkers for Detection of Chronic Kidney Diseases in Obese and Overweight Egyptian Children

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

-

Abstract

World Health Organization (WHO) reports that kid obesity is a major problem for international health, particularly in low- and middle-income nations. Also, significant growth retardation in children is often caused by chronic renal illness (CKD); Objectives: This study aimed to evaluate the efficacy of estimated glomerular filtration rate and microalbuminuria in detecting chronic renal disease in overweight and obese Egyptian children. Patients and Methods: The participants in this cross-sectional research were 138 children aged 5 – 18 years. According to their BMI, there were 45 clinically healthy children as a control group, 43 overweight children and 50 obese children; Results: according to eGFR, there were 14 children (32.6%) with CKD in the overweight group and that there were 24 children (48%) with CKD in the obese group. Although the prevalence of CKD was higher in the obese group. According to microalbuminuria, there were 8 children (18.6%) with CKD in the overweight group while there were 15 children (30%) with CKD in the obese group. The prevalence of CKD was higher in the obese group, Conclusion: We find that the serum creatinine, serum urea, and albumin in urine levels are all significantly higher in the obese and overweight groups, whereas the eGFR is significantly lower. The eGFR increased with age and height in a statistically meaningful way. The eGFR was also inversely related to body mass index, creatinine, urea, white blood cell count, and creatinine in the urine. Moreover, there was a favourable connection between albumin/creatinine ratio and diastolic blood pressure

DOI

10.21608/bmfj.2023.208065.1808

Keywords

Glomerular Filtration Rate, Microalbuminuria, chronic kidney diseases, obese, overweight

Authors

First Name

Hana

Last Name

Omar

MiddleName

Ramadan

Affiliation

Department of Pediatrics, Faculty of Medicine- Benha University

Email

hanaaramadan250@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Rashad

MiddleName

Mahmoud

Affiliation

Department of Pediatrics , Faculty of Medicine- Benha University

Email

mmrashad2002@gmail.com

City

-

Orcid

-

First Name

Eman

Last Name

Abd Elgwad

MiddleName

Ramadan

Affiliation

Department of Clinical and chemical pathology, Faculty of Medicine-Benha

Email

emanramdan2023@gmail.com

City

-

Orcid

-

First Name

Mai Atef Abdelhamid

Last Name

Abdelhamid

MiddleName

Atef

Affiliation

Depatement of Pediatrics department, Faculty of Medicine- Ain Shams University

Email

atefmandy215@gmail.com

City

-

Orcid

-

Volume

40

Article Issue

2

Related Issue

43348

Issue Date

2023-09-01

Receive Date

2023-04-30

Publish Date

2023-09-01

Page Start

542

Page End

552

Print ISSN

1110-208X

Online ISSN

2357-0016

Link

https://bmfj.journals.ekb.eg/article_315817.html

Detail API

https://bmfj.journals.ekb.eg/service?article_code=315817

Order

21

Type

Original Article

Type Code

787

Publication Type

Journal

Publication Title

Benha Medical Journal

Publication Link

https://bmfj.journals.ekb.eg/

MainTitle

Estimated Glomerular Filtration Rate and Microalbuminuria as Biomarkers for Detection of Chronic Kidney Diseases in Obese and Overweight Egyptian Children

Details

Type

Article

Created At

24 Dec 2024