Background: Environmental lead exposure as a risk factor for chronic kidney disease (CKD) we evaluated the association between lead exposure and CKD.
Aim of the study: The aim of the study to assess lead in the drinking water and blood lead level in children with chronic kidney disease.
Subjects and Methods: This case and control study included 30 cases diagnosed with chronic kidney disease on hemodialysis, 10 cases diagnosed with chronic kidney disease and on conservative therapy according to Schwartz formula and 10 healthy children as controls. All subjects were subjected to detailed history taking, general examination, and laboratory investigations. Also, examination for signs of lead poising and measurement of lead in blood and water were performed. Results: Our study showed that a male predominance. lead was significantly increased in cases compared to controls, and that was evident in both blood and water lead Urea and Creatinine was significantly increased in cases compared to controls (p < 0.001) GFR was significantly lowered in cases compared to controls (p < 0.001) The study revealed positive correlation between blood lead ,Urea and Creatinine (p < /p>