Background: Endometrial cancer is the commonest gynecological neoplasm in developed nations. The current study aimed at comparing, in a series of females the usefulness, security as well as morbidity of total LPS and LPT for early-stage EC.

Methods: This prospective randomized study of 50 females with clinical stage I endometrial carcinoma. cases were classified into 2 equal groups: group 1 was managed by total LPS, and group 2 were treated with LPT. At admission, each woman was subjected to a gynecological and rectal examination, US and hysteroscopic evaluation. biopsies from the endometrium, chest X-ray, and MRI and/ or CT scan. LN dissection was done in selected patients in both groups.

Results: Characteristics of the studied groups (Hb decline, blood loss and time of postoperative ileus) revealed significant reduction in the LPS group in comparison with LPT group. The incidence of fever revealed a significant decrease in LPS group compared to LPT group as well. Hospital stay and operative time were insignificantly different between the studied groups. The incidence of fever was significantly lower in LPS group compared to LPT group. Complications including (bladder and ureteric injuries, conversion to laparotomy, missed intestinal injury, postoperative hematoma, and wound infection) were insignificantly different between the studied groups.

Conclusions: Laparoscopy is an appropriate method in treating early endometrial carcinoma .

Keywords: Laparoscopic Hysterectomy, Laparoscopic Lymphadenectomy, Conventional Abdominal Hysterectomy, Endometrial Cancer