Abstract

Background

Predictors of mortality in acute coronary syndrome are crucial in clinical practice since coronary artery disease is the leading cause of death worldwide.

Purpose

to assess the value of triglyceride glucose index (TyG) in prediction of major adverse cardiac events (MACE) in patients with acute coronary syndrome.

Materials and methods

We conducted a prospective study on 104 acute coronary syndrome patients admitted at Sohag university hospital coronary care unit and followed up those patients for 6months for recording of major adverse cardiac events after measuring triglyceride glucose index on admission.

Results

following up patients for major adverse cardiac events, the results showed that heart failure was reported in 9 (8.7%) cases, myocardial infarction was reported in 4 (3.8%) cases while stroke was found in one case.

The most frequent comorbidity found among the studied patients was DM that was found in 76.9% cases followed by hypertension in 41.3% cases.

The age of studied patients ranged from 35 to 78 years with mean age (±SD) was 58.81± 9.82 years. triglyceride and glucose index (TyG index) ranged from 7.4 to 10.4 with mean (±SD) was 8.30± 0.60.

There was significant elevation in TyG index in cases with major adverse cardiac effects with mean index of 9.23 in patients with heart failure, 10.03 in patients with myocardial infarction and 10.30 in the patient with stroke.



Conclusion

The study concluded that higher TyG index values are an independent predictor for increased risk of MACEs in ACS patients within six months of ACS.