Introduction: The maxillary sinus is part of the naso-maxillary complex and in close proximity to the upper teeth; it is of interest to all clinicians and practitioners in the dental field including orthodontists. Studies were conducted to evaluate how the maxillary sinus may affect the orthodontist's treatment plan. Aim: The present study was designed to identify whether a relation exists between the maxillary sinus volume and different anteroposterior maxillary growth patterns in adults using cone beam computed tomography. Materials and methods: Ninety full skull CBCT scans were divided into three equal groups according to the anteroposterior maxillary growth pattern; normal maxilla, excess maxilla and deficient maxilla. The maxillary sinus volume was measured in both the right and left side using OnDemand3D. Results: The results of the study revealed no significant difference between the maxillary sinus volume in the different groups of anteroposterior maxillary growth pattern. Additionally, there was no significance difference between the volume of the maxillary sinus between the right and left sides. Conclusions: Different anteroposterior maxillary growth patterns do not affect the total adult volume of the maxillary sinus. The right and left maxillary sinus in adult populations show similar volumes with negligible differences between both sides.