Introduction: Internal derangement of the temporomandibular joint is the
term used to describe a pathologic entity that obstructs the smooth function of the
temporomandibular joint. Arthrocentesis is most used in patients not responding to
conservative approach. Aim: The aim of study was designed to compare between
cyclooxygenase-2inhibitor (meloxicam) and non-steroidal anti-inflammatory
(piroxicam) in the management of patients with TMJ internal derangement.
Patients and methods: The present study was conducted on 12 adult joints with
impaired jaw movements, limited joint function, limited mouth opening, pain with
movement of the temporomandibular joint and TMJ noise (Clicking at the affected
joint) and divided randomly into two equal groups 6 joints in each group. Group 1:
where arthrocentesis were performed for the affected joint followed by intraarticular
injection of one ml of piroxicam. Group 2: where arthrocentesis were performed
for the affected joints followed by intraarticular injection of one ml. of Meloxicam.
Results: Intra-articular injection of piroxicam is effective more than Meloxicam
in long term management of pain of the joints and both of them give statistically
significant result in both management of clicking sound and mouth opening.
Conclusion: Arthrocentesis followed by piroxicam is safe and more effective than
Meloxicam treatment of temporomandibular joint dysfunction.