Introduction: Ozone can react with blood components and positively affect oxygen metabolism, cell energy, the immunomodulatory property, antioxidant defense system, and microcirculation in tissues. In dental surgery, ozone may be useful to promote hemostasis, enhance local oxygen supply, and inhibit bacterial growth. The use of ozone has been proposed in dentistry because of its antimicrobial, disinfectant, and healing properties. Aim: To assess the influence of topical ozone administration on patient comfort after third molar surgery.
Material and Methods: Forty patients with lower impacted third molar that need surgical extraction were selected and divided randomly into two equal groups: Group(I), patients were subjected to odontectomy of impacted mandibular 3rd molar. Group (II), patients were subjected to odontectomy of the impacted mandibular 3rdmolar followed by the application of ozone gel into the socket. The follow-up visits were performed where the intensity of pain, the symptoms of trismus, swelling and radiographic bone density were evaluated.
Results: Group II showed statistical significant difference of pain compared to group I while both groups showed no statistical significant difference with regard to swelling and trismus and radiographic bone density.
Conclusion: Ozone gel application therapy was useful for the reduction of postoperative pain and increased quality of life after odontectomy of mandibular third molar. However, it had no effect on either post-operative swelling or trismus in addition to bone density