Introduction: Egypt lacks awareness regarding the positive influence of reflexology along with aerobic training (AT) on the quality of life (QoL) of patients with hypertension (HTN).

Objective: We aim to determine reflexology and AT effects on the insomnia severity index (ISI) and QoL of HTN patients.

Methods: This study enrolled 40 HTN female patients aged 35–45 years who were equally divided into groups A and B. Groups A and B participants were provided with medications and peddling training, while Group B participants also received reflexology. The treatment protocol consisted of an eight-week program with three sessions per week. After the four-week treatment protocol, a post-evaluation (post-1) was conducted and was repeated after another four-week treatment (post-2). The participants underwent assessment for systolic and diastolic blood pressure, ISI, and a 36-item short-form survey (SF-36), a general QoL measure, pre- and post-treatment.

Results: The results revealed significant discrepancies in the assessed variable between both groups pre- and post-treatment (post-1/2). When comparing the post-treatment values (post-1/2) of the evaluated variable between groups A and B, incorporating reflexology and AT, such as peddling training, into the physical treatment program is recommended.

Conclusion: The study highlights the positive impact of reflexology and AT on the QoL and ISI of female HTN patients, recommending their incorporation into treatment programs.