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288659

Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC

Article

Last updated: 24 Dec 2024

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Tags

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Abstract

Hepatocellular carcinoma (HCC), the fifth most common kind of cancer in the world, is a significant public health concern in Egypt. The development of HCC has been linked to genetic diversity, making the disease challenging to treat. The bulk of the chronic liver illnesses that 95% of HCC patients suffer started by viruses. HCC is a complicated condition. One of the origins of HCC is the hepatitis C virus (HCV). Though being branded to piece a part in a variety of biological courses and having evidence portentously together a carcinogenic and a preemptive influence on the liver, the importance of ERa in the expansion of HCC remains doubtful. It has been shown that those with HCV have a high level of ERa expression. This study reveals how ERa and its variants affect how hepatocarcinogenesis develops.

DOI

10.21608/eajbsg.2023.288659

Keywords

Hepatocellular carcinoma (HCC)

Authors

First Name

Mahmoud

Last Name

Amer

MiddleName

-

Affiliation

Botany and Microbiology Department, Faculty of Science, Benha University, Benha, Egypt.

Email

mahmoud.amer@fsc.bu.edu.eg

City

Egypt

Orcid

-

First Name

Alaa

Last Name

Elmetwalli

MiddleName

-

Affiliation

Department of Clinical Trial Research Unit and Drug Discovery, Egyptian Liver Research Institute and Hospital (ELRIAH), Mansoura, Egypt.

Email

alaa.elmetwalli@outlook.com

City

Egypt

Orcid

-

First Name

Attia

Last Name

Attia

MiddleName

A.

Affiliation

Botany and Microbiology Department, Faculty of Science, Benha University, Benha, Egypt.

Email

-

City

Egypt

Orcid

-

First Name

Ayman

Last Name

Hassan

MiddleName

-

Affiliation

Department of Medical Research and Diagnostic Labs, Egyptian Liver Research Institute and Hospital, Mansoura, Egypt

Email

-

City

Egypt

Orcid

-

First Name

Mohamed

Last Name

Nasr Eldin

MiddleName

A.

Affiliation

Botany and Microbiology Department, Faculty of Science, Benha University, Benha, Egypt.

Email

-

City

Egypt

Orcid

-

Volume

15

Article Issue

1

Related Issue

38907

Issue Date

2023-06-01

Receive Date

2022-12-16

Publish Date

2023-02-20

Page Start

61

Page End

66

Print ISSN

2090-0872

Online ISSN

2090-0880

Article File

EAJBSG_Volume 15_Issue 1_Pages 61-66.pdf

PDF . 596.9kB

Link

https://eajbsg.journals.ekb.eg/article_288659.html

Detail API

https://eajbsg.journals.ekb.eg/service?article_code=288659

Order

288,659

Type

Original Article

Type Code

689

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, G. Microbiology

Publication Link

https://eajbsg.journals.ekb.eg/

MainTitle

Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC

Details

Type

Article

Created At

24 Dec 2024