Aim: The aim of this study was to evaluate the fit of CAD\CAM frameworks deigned based on virtual implant positions versus actual implant positions.
Subjects and methods: Five models with 20 frameworks were included. Their cone-beam computerized tomographic images were Planmeca Imaging System and their intraoral surface scans with Medit scanner. The data from these two sources were then merged; the volumetric topography of models was constructed and prosthesis/implant planning was performed using RealGuide software. From these plans, fully computer guided surgical templates and screw-retained Final metal prostheses were manufactured before implant placements using computer–aided design/computer–aided manufacturing process. Jdental implants were placed fully guided, the prostheses were inserted and evaluated based on their time spent for construction. The control group was frameworks done by the conventional technique by scanning the scan bodies of actual implant positions after implant placement.
Results showed that the difference between the two groups was  not statistically significant was reported between two groups regarding fit of frameworks.
Conclusion: Preoperative frameworks have the same fit as the postoperative frameworks.