Beta
367463

Clinical and Histological Diversity of Ossifying Fibroma: A Series of 4 Cases Showing Aggressive Behavior

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

Oral Pathology

Abstract

Aim: Juvenile Ossifying Fibroma (JOF) is a variant of ossifying fibroma. It occurs in young age group 5-18 years old causing sever malocclusion, encroaching vital anatomical areas. Commonly presented with rapid alarming growth. Two histopathological patterns are linked to the aggressive biological behavior namely juvenile trabecular ossifying fibroma (JTOF) and psammomatoid ossifying fibroma (POF). JTOF mostly affects children and adolescents with equal gender and site distribution between the mandible and maxilla. While POF occurs chiefly in extra-gnathic sites, especially in paranasal sinuses, periorbital bones and skull base. Surgery with wide excision is the optimal treatment. Subjects & methods: This article presents detailed review concerning clinical radiographic and histopathological examination of four cases. The age range of the patients studied was between 7 and 22 years with reflection to treatment protocol and prognosis. Results: The conditions observed in these cases primarily affected the maxilla, extending towards the floor of the orbit and, in some instances, the nasal septum. In other cases, the conditions were in the mandible. Conclusion: OF is a benign tumor having aggressive subtypes with high recurrence rates. For accurate diagnosis, it is crucial to examine the clinical, radiographic, and histopathological aspects of the lesions because they share similar characteristics with other aggressive bone abnormalities. Early detection and an appropriate treatment strategy involving enucleation with curettage or resection of the tumour according to the size of the lesion, followed by long-term follow-up, are essential for optimal outcomes.

DOI

10.21608/adjc.2024.246884.1420

Keywords

ossifying fibroma, bone neoplasms, treatment

Authors

First Name

Shymaa

Last Name

Hamza

MiddleName

ahmed

Affiliation

Oral and Maxillofacial Pathology, Faculty of Dentistry, Cairo University, Cairo, Egypt.

Email

shymaa.hamza@dentistry.cu.edu.eg

City

Giza

Orcid

-

First Name

Hadeel

Last Name

mohamed

MiddleName

Ahmed

Affiliation

Oral pathology, Misr International University, Cairo, Egypt.

Email

hadeel.mohamed@dentistry.cu.edu.eg

City

Giza

Orcid

-

First Name

Shaimaa

Last Name

Zayed

MiddleName

omar

Affiliation

Oral maxillofacial pathology, faculty of dentistry, Cairo University

Email

shaimaa.omar@dentistry.cu.edu.eg

City

Giza

Orcid

0000-0002-6559-0609

Volume

6

Article Issue

3

Related Issue

48861

Issue Date

2024-07-01

Receive Date

2023-11-09

Publish Date

2024-07-01

Page Start

568

Page End

580

Print ISSN

2636-302X

Online ISSN

2636-3038

Link

https://adjc.journals.ekb.eg/article_367463.html

Detail API

https://adjc.journals.ekb.eg/service?article_code=367463

Order

367,463

Type

Case Reports

Type Code

692

Publication Type

Journal

Publication Title

Advanced Dental Journal

Publication Link

https://adjc.journals.ekb.eg/

MainTitle

Clinical and Histological Diversity of Ossifying Fibroma: A Series of 4 Cases Showing Aggressive Behavior

Details

Type

Article

Created At

24 Dec 2024