339062

Solitary Fibrous Tumor: A Case with a Review

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Oral Pathology

Abstract

solitary fibrous tumor (SFT) is a rare intraoral occurring tumor. Buccal mucosa is among the most commonly affected sites. SFT lesions are linked to a NAB2-STAT6 fusion gene. The lesion exhibits well circumscribed feature in both radiographical and histopathological examinations. The lesion shows STAT 6, CD34, bcl-2 and CD99 positive expression. Unfortunately STAT6 and CD 34 expression are lost in highly malignant lesions, making the diagnosis challenging. The reported case is a 43 –year- old female presented with a painful lesion in the left buccal mucosa. Upon surgical excision and histopathological examination the lesion revealed a bland spindle cell lesion with nuclear STAT6 and beta catenin cytoplasmic reactivity. After excision the case was followed up for 6 months and showed no recurrence. This case showed a typical presentation the same as the literature reported cases. However, the associated pain was coming in contrast to the most published cases. Although being usually negative in SFT, beta catenin showed cytoplasmic reactivity in our presented case.

DOI

10.21608/adjc.2023.213419.1316

Keywords

Solitary Fibrous Tumor (SFT), Hemangiopericytoma, Spindle cell lesion

Authors

First Name

Enjy

Last Name

Bassim

MiddleName

Abdelrazek

Affiliation

Assistant Lecturer of Oral Pathology Cairo, Egypt

Email

enjy.bassim@dentistry.cu.edu.eg

City

-

Orcid

0000-0002-0493-6282

First Name

Hatem

Last Name

Amer

MiddleName

-

Affiliation

Department of oral and maxillofacial pathology, Faculty of dentistry, Cairo university, Cairo, Egypt.

Email

hatemamer@dentistry.cu.edu.eg

City

Cairo

Orcid

-

First Name

Shymaa

Last Name

Hamza

MiddleName

-

Affiliation

Oral and Maxillofacial Pathology, Faculty of Dentistry, Cairo University, Cairo, Egypt. Oral and Maxillofacial Pathology, Faculty of Dentistry, NewGiza University, Giza, Egypt.

Email

shymaa.hamza@dentistry.cu.edu.eg

City

Cairo

Orcid

-

Volume

6

Article Issue

1

Related Issue

45243

Issue Date

2024-01-01

Receive Date

2023-05-25

Publish Date

2024-01-01

Page Start

175

Page End

180

Print ISSN

2636-302X

Online ISSN

2636-3038

Link

https://adjc.journals.ekb.eg/article_339062.html

Detail API

https://adjc.journals.ekb.eg/service?article_code=339062

Order

339,062

Type

Case Reports

Type Code

692

Publication Type

Journal

Publication Title

Advanced Dental Journal

Publication Link

https://adjc.journals.ekb.eg/

MainTitle

Solitary Fibrous Tumor: A Case with a Review

Details

Type

Article

Created At

24 Dec 2024