Dental caries continues to be the most prevalent chronic disease across the world despite advances in prevention and treatment options. Caries management has shifted from the traditional approach to minimum intervention dentistry, that frequently use fluoridated and antimicrobial agents. Among these agents, silver diamine fluoride (SDF) has gained significant recognition due to its antibacterial properties and ability to remineralize carious lesions. It has been used as anti-caries agent and dentin desensitizer for hundreds of years around the world. SDF is an effective, inexpensive, and non- invasive option for children with high caries risk, special health care needs and those with behavioral or medical management problems. Its application is simple and requires no expensive equipment. No adverse systemic effects due to SDF application have been reported. However black staining of tooth structure following its application is a matter of concern. The current review gives insight of the action and clinical application of SDF based on published literature.