The land snails cause damage to their host plants, by feeding on leaves, blooms, flowers, fruits, trunks, limbs and barks. Thus, necessary to control these pests.
            Phasmarhabditis eagyptiaca Azzam 2023 is a new species of snail parasitic nematode, which was recorded and described to investigate its capability to infect some snails and slugs.
           This investigation aims to prove the parasitization  of the P. eagyptiaca nematode on Eobania vermiculata (Müller, 1774) and clear its effect on snails consequently suitability of the nematodes for application to control gastropods, also to differentiate between the two strains of E. vermiculata.Two strains of Eobania snails were infected with the snail parasitic nematodes P. eagyptiaca. The differences between infected and non-infected snails in histological and protein pattern alterations were investigated.Immunoreactivity as fibroblast region and splitting necrosis and degeneration regions were observed in the head foot, ovary, testis, and digestive gland in the two strains of infected E. vermiculata, in addition to changes in protein patterns. All these alterations lead to snail death.
The histopathological alterations in E vermiculata snails infected with snail parasitic nematode P eagyptiaca confirm the parasitic relation between them. Although the immune defense from snails against the parasitic nematodes, the nematodes could kill the snails. This indicates the suitability of this nematode for land gastropods biocontrol.