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322409

Study the Hypersensitivity Type 1 in Patients Suffering from Drug and Asthma Allergy

Article

Last updated: 03 Jan 2025

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Abstract

The current study was conducted to measure some immunoglobulin IgE, IgG, IgM, some interleukins interleukin 4 (IL-4), interleukin 5 (IL-5) and a complete blood count (CBC) in patients suffering from hypersensitivity type 1 (drug allergy, and asthma). The study began from 1/9/2022 to 1/3/2023 and included 59 people of all ages. The current results showed that people with drug allergy and asthma had an increase in the concentration of IL-4 (407.8 ±27.0), (837.6 ± 29.4), IL-5 (323.1 ±39.7) (568.4 ± 32.1) respectively. The level of IgE, IgG and IgM was elevated in patients suffering from drug allergies (11.2±2.6) (18.1±2.8) (and 47.9±5.3) respectively and asthma was (30.3±3.4), (26.1 ± 4.6) and  (50.2 ± 8.6) respectively.
           The results of the complete blood count showed a significant increase in the white blood cells, Eosinphile. In addition to many differences in blood parameters compared to normal proportions. It was also found that the IgE concentration decreased with age, while the IgG antibody concentration increased compared to the standard sample and with the increase in age groups. 

DOI

10.21608/eajbsc.2023.322409

Keywords

Hypersensitivity, IgE, IgG, IgM, IL-4, IL-5, CBC

Authors

First Name

Asmaa

Last Name

Mahmood

MiddleName

E.

Affiliation

Department of Pathological Analysis, College of Applied Sciences, University of Samarra, Iraq

Email

asma.kurkum@uosamarra.edu.iq

City

Iraq

Orcid

-

First Name

Hajar

Last Name

Rasheed

MiddleName

K.

Affiliation

Department of Pathological Analysis, College of Applied Sciences, University of Samarra, Iraq

Email

-

City

Iraq

Orcid

-

Volume

15

Article Issue

2

Related Issue

42345

Issue Date

2023-12-01

Receive Date

2023-09-17

Publish Date

2023-10-25

Page Start

503

Page End

512

Print ISSN

2090-0767

Online ISSN

2090-083X

Link

https://eajbsc.journals.ekb.eg/article_322409.html

Detail API

https://eajbsc.journals.ekb.eg/service?article_code=322409

Order

322,409

Type

Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

MainTitle

Study the Hypersensitivity Type 1 in Patients Suffering from Drug and Asthma Allergy

Details

Type

Article

Created At

24 Dec 2024