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303332

Molecular Evaluation of Long Non-Coding RNA (TUG1) in Systemic Lupus Erythematosus

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Last updated: 03 Jan 2025

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Abstract

Long non-coding RNAs play an important role in systemic lupus erythematosus. Our work purpose is to evaluate the level of LNC (TUG1) in SLE patients. This research includes 20 control and 70 SLE subjects. The serum level of LNC (TUG1) was measured by polymerase chain reaction. Down-expression of LNC (TUG1) was observed in SLE patients more than in control. A significant AUC of TUG1 level was recorded, which recommended that (TUG1) can act as a new biomarker for SLE determination.

DOI

10.21608/eajbsc.2023.303332

Keywords

SLE, Long non-coding RNA, TUG1, biomarker

Authors

First Name

Shimaa

Last Name

Ramadan

MiddleName

S.

Affiliation

Biochemistry Division, Chemistry Department, Faculty of science, Helwan University, Cairo, Egypt.

Email

-

City

Egypt

Orcid

-

First Name

Wafaa

Last Name

Shousha

MiddleName

Gh.

Affiliation

Biochemistry Division, Chemistry Department, Faculty of science, Helwan University, Cairo, Egypt.

Email

-

City

Egypt

Orcid

-

First Name

Olfat

Last Name

Shaker

MiddleName

G.

Affiliation

Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Email

olfat.shaker@kasralainy.edu.eg

City

Egypt

Orcid

-

First Name

Nagham

Last Name

Ahmed

MiddleName

H.

Affiliation

Biochemistry Division, Chemistry Department, Faculty of science, Helwan University, Cairo, Egypt.

Email

dr.nagham2010@gmail.com

City

Egypt

Orcid

-

First Name

Sara

Last Name

Abdo

MiddleName

M.

Affiliation

Biochemistry Division, Chemistry Department, Faculty of science, Helwan University, Cairo, Egypt.

Email

-

City

Egypt

Orcid

-

Volume

15

Article Issue

1

Related Issue

38909

Issue Date

2023-06-01

Receive Date

2023-04-23

Publish Date

2023-06-08

Page Start

497

Page End

501

Print ISSN

2090-0767

Online ISSN

2090-083X

Article File

EAJBSC_Volume 15_Issue 1_Pages 497-501.pdf

PDF . 431.3kB

Link

https://eajbsc.journals.ekb.eg/article_303332.html

Detail API

https://eajbsc.journals.ekb.eg/service?article_code=303332

Order

303,332

Type

Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

MainTitle

Molecular Evaluation of Long Non-Coding RNA (TUG1) in Systemic Lupus Erythematosus

Details

Type

Article

Created At

24 Dec 2024