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287545

Epidemiological Aspect of Colorectal cancer: A Retrospective Study in Sidi-Bel-Abbes Wilaya, Western Algeria

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Last updated: 24 Dec 2024

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Abstract

Background: Colorectal cancer (CRC) is considered the third most common cancer worldwide, the second leading cause of death and represents a major public health problem in many countries.  Patients and Methods: We undertook a retrospective study survey by reviewing files from the Medical Oncology Department of  Hassani Abdelkader Hospital of Sidi Bel Abbes, during a period from January 2011 to February 2016, with the aim of studying the epidemiological, clinical, anatomopathological and therapeutic aspects of CRC. Results: a total of 236 patients of both sexes suffering from CRC were involved, Our study revealed a significant increase in incidence, a male predominance (sex ratio = 1.27), and a prevalent age range between 45-60 years old with a mean age of 58.25±13.78. Colon cancer represents 2/3, and rectal cancer represents 1/3 of our sample (respectively: 67, 8% and 32, 2%). Tobacco and alcohol consumption were studied as risk factors. Loss of weight, asthenia, anorexia, transit disorders, abdominal pain and faecal blood were the main involved clinical signs. We recorded a predominance of budding tumor forms (44.44%). Histologically: well-differentiated adenocarcinoma type is the most common (55%). We noted the presence of liver and lung metastases mainly. 76% of our patients underwent surgery, and Adjuvant chemotherapy was the main treatment for this type of cancer. Conclusion: According to the present study, we can affirm that our patients were victims of a late diagnosis due to the ignorance of their pathology, which unfortunately was already present at the time of the examinations

DOI

10.21608/eajbsc.2023.287545

Keywords

colorectal cancer, Retrospective study, clinicopathological factors, anatomopathological characteristics, Therapy

Authors

First Name

Karouaz

Last Name

Lilia

MiddleName

-

Affiliation

Department of Biology, Faculty of Life and Natural Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria. -Laboratory of Molecular Microbiology Proteomics and Health, Djillali Liabes University, Sidi-Bel-Abbes, Algeria.

Email

karouaz.liliag@gmail.com

City

Algeria

Orcid

-

First Name

Haoud

Last Name

Khadidja

MiddleName

-

Affiliation

Department of Biology, Faculty of Life and Natural Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria. -Laboratory of Molecular Microbiology Proteomics and Health, Djillali Liabes University, Sidi-Bel-Abbes, Algeria.

Email

haoud_khadija82@yahoo.fr

City

Algeria

Orcid

-

First Name

Drici

Last Name

El-Mokhtar

MiddleName

Amine

Affiliation

Department of Biology, Faculty of Life and Natural Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria.

Email

-

City

-

Orcid

-

First Name

Ouali

Last Name

Sihem

MiddleName

-

Affiliation

Department of Biology, Faculty of Life and Natural Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria. -Laboratory of Molecular Microbiology Proteomics and Health, Djillali Liabes University, Sidi-Bel-Abbes, Algeria.

Email

-

City

-

Orcid

-

First Name

Bouzid

Last Name

Souad

MiddleName

-

Affiliation

Department of Biology, Faculty of Life and Natural Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria.

Email

-

City

Algeria

Orcid

-

First Name

Aissani

Last Name

Ikram

MiddleName

-

Affiliation

Department of Biology, Faculty of Life and Natural Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria.

Email

-

City

-

Orcid

-

First Name

Mehida

Last Name

Hayet

MiddleName

-

Affiliation

Department of Biology, Faculty of Life and Natural Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria.

Email

-

City

-

Orcid

-

First Name

Bereksi

Last Name

Faiza

MiddleName

Reguig

Affiliation

Department of Medical Oncology, University Hospital Center, Sidi-Bel-Abbes, Algeria

Email

-

City

Algeria

Orcid

-

Volume

15

Article Issue

1

Related Issue

38909

Issue Date

2023-06-01

Receive Date

2022-12-03

Publish Date

2023-02-27

Page Start

161

Page End

166

Print ISSN

2090-0767

Online ISSN

2090-083X

Article File

EAJBSC_Volume 15_Issue 1_Pages 161-166.pdf

PDF . 507.1kB

Link

https://eajbsc.journals.ekb.eg/article_287545.html

Detail API

https://eajbsc.journals.ekb.eg/service?article_code=287545

Order

287,545

Type

Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

MainTitle

Epidemiological Aspect of Colorectal cancer: A Retrospective Study in Sidi-Bel-Abbes Wilaya, Western Algeria

Details

Type

Article

Created At

24 Dec 2024