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290569

Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria

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Last updated: 24 Dec 2024

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Abstract

Anvillea radiata is used in traditional medicine for the treatment of chest colds, indigestion, and gastrointestinal disorders. Our plant has hypoglycaemic, antitumor, anti-inflammatory, and antibacterial activity and is used for the treatment of dysentery.
            We have investigated the analgesic and anti-inflammatory activity of the aqueous extract of Anvillea radiata. In analgesic activity, we have used mice of the strain NMRI Albinos, weighing between 26 and 38 g (in vivo study). Acetic acid was used to induce writhes in mice, and the evaluation of the analgesic activity shows that the aqueous extract at 150 mg/kg of our plant induces a decrease in the number of abdominal cramps caused by 1% acetic acid. The aqueous extract of our plant has an analgesic effect almost equal to that of Diclofenac; in fact, the latter causes a pain inhibition of 30.28 1.1% and that of Anvillea radiata of 28.71  2.1% for a concentration of 150 mg/ kg. Our results of this research indicated that Anvillea radiata inhibited inflammation, which could explain its use in traditional medicine.

DOI

10.21608/eajbsz.2022.290569

Keywords

Anvillea radiata, analgesic activity, anti-inflammatory activity, Aqueous extract

Authors

First Name

Fyad

Last Name

khadidja

MiddleName

-

Affiliation

Laboratory of Bioactive Molecules and Chiral Separation (LMBSC) University of Bechar, Bechar, Algeria.

Email

-

City

Algeria

Orcid

-

First Name

Belboukhari

Last Name

nasser

MiddleName

-

Affiliation

Laboratory of Bioactive Molecules and Chiral Separation (LMBSC) University of Bechar, Bechar, Algeria.

Email

-

City

Algeria

Orcid

-

First Name

Aici

Last Name

djahida

MiddleName

-

Affiliation

Department of Exact Sciences, Normal Higher School, Bechar- 08000, Algeria.

Email

-

City

Algeria

Orcid

-

First Name

Abdelkader

Last Name

Ammam

MiddleName

-

Affiliation

Laboratory of Pharmacognosy, Bio toxicology, and Biological Valorization of Plants, Moulay Tahar University, BP 20000, Saida, Algeria.

Email

vetokadi@yahoo.fr

City

Algeria

Orcid

-

First Name

Belmamoun

Last Name

Reda

MiddleName

Ahmed

Affiliation

Laboratory of Process, materials and environmental engineering, Djillali Liabes University, BP 22000, Sidi-Bel-Abbes, Algeria.

Email

-

City

Algeria

Orcid

-

First Name

Ghouti

Last Name

dalila

MiddleName

-

Affiliation

Laboratory of Pharmacognosy, Bio toxicology, and Biological Valorization of Plants, Moulay Tahar University, BP 20000, Saida, Algeria.

Email

-

City

Algeria

Orcid

-

First Name

Boukabene

Last Name

kheira

MiddleName

Fouzia

Affiliation

Laboratory of Animal Production Sciences and Techniques, Mostaghanem; Moulay Tahar University, BP 20000, Saida, Algeria.

Email

-

City

Algeria

Orcid

-

Volume

14

Article Issue

2

Related Issue

35359

Issue Date

2022-12-01

Receive Date

2022-09-23

Publish Date

2022-12-06

Page Start

473

Page End

479

Print ISSN

2090-0759

Online ISSN

2090-0821

Article File

EAJBSZ_Volume 14_Issue 2_Pages 473-479.pdf

PDF . 520.6kB

Link

https://eajbsz.journals.ekb.eg/article_290569.html

Detail API

https://eajbsz.journals.ekb.eg/service?article_code=290569

Order

290,569

Type

Original Article

Type Code

672

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, B. Zoology

Publication Link

https://eajbsz.journals.ekb.eg/

MainTitle

Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria

Details

Type

Article

Created At

24 Dec 2024