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358826

Antioxidant and Anticoagulant Activities of Red Palm Weevil, Rhynchophorus ferrugineus (Coleoptera: Curculionidae) Extracts

Article

Last updated: 24 Dec 2024

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Abstract

The study focused on analyzing the antioxidant properties of extracts from red palm weevil larvae Rhynchophorus ferrugineus, obtained using hexane, n-butanol, dichloromethane, and diethyl ether. Additionally, the anticoagulant effects of these extracts were evaluated through activated partial thromboplastin time (APTT) and prothrombin time (PT) assays. Results showed that the hexane, n-butanol, dichloromethane, and diethyl ether extracts from Rh. ferrugineus larvae exhibited antioxidant activity comparable to ascorbic acid, with IC50 values of 142.67, 122.24, 231.77 and 74.95 µg/ml, respectively, compared to 3.16 µg/ml for ascorbic acid. Also, the anticoagulant activity of Rh. ferrugineus (larvae) tested extracts using APTT assay showed 33.8, 44.3 and 50.9 sec. At 25, 50 and 75 µg/ml of hexane extract, respectively. Meanwhile, Rh. ferrugineus n-butanol extract recorded 46.9, 57.2 and 65.5 sec. At the same concentrations. Also, dichloromethane and diethyl ether recorded anticoagulant activity reached 31.2, 40.6, 48.7 and 44.3, 52.9, 62.1 sec. at 25, 50 and 75 µg/ml, respectively, vs. 59.8, 86.2 and 109.7 sec. For the Heparin sodium salt, use the same concentrations. Generally, all Rh. ferrugineus larval extracts tested proved to be antioxidant agents. The anticoagulant potential of Rh. ferrugineus tested extracts were weaker than those of heparin and needed more concentration to reach the commercial anticoagulant (Heparin sodium salt) in both assays (APTT and PT).    

DOI

10.21608/eajbsa.2024.358826

Keywords

Rhynchophorus ferrugineus, antioxidant, Anticoagulant, extracts

Authors

First Name

Hossam

Last Name

Ahmed

MiddleName

A.R.

Affiliation

Department of Zoology, Faculty of Science, Al-Azhar University, Cairo 11651, Egypt.

Email

hossam.abdelrahman2024@gmail.com

City

Egypt

Orcid

-

First Name

Mostafa

Last Name

Hassan

MiddleName

I.

Affiliation

Department of Zoology, Faculty of Science, Al-Azhar University, Cairo 11651, Egypt.

Email

-

City

Egypt

Orcid

-

First Name

Ahmed

Last Name

Shehata

MiddleName

Z.I.

Affiliation

Department of Zoology, Faculty of Science, Al-Azhar University, Cairo 11651, Egypt.

Email

-

City

Egypt

Orcid

-

Volume

17

Article Issue

2

Related Issue

47242

Issue Date

2024-06-01

Receive Date

2024-05-06

Publish Date

2024-06-10

Page Start

59

Page End

67

Print ISSN

1687-8809

Online ISSN

2090-0813

Link

https://eajbsa.journals.ekb.eg/article_358826.html

Detail API

https://eajbsa.journals.ekb.eg/service?article_code=358826

Order

358,826

Type

Original Article

Type Code

667

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. A, Entomology

Publication Link

https://eajbsa.journals.ekb.eg/

MainTitle

Antioxidant and Anticoagulant Activities of Red Palm Weevil, Rhynchophorus ferrugineus (Coleoptera: Curculionidae) Extracts

Details

Type

Article

Created At

24 Dec 2024