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308016

Erythrina Alkaloids: An Updated Review with Neurological Perspective.

Article

Last updated: 03 Jan 2025

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Tags

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Abstract

Erythrina is a genus comprising several plant species that are distributed in tropical and subtropical regions. This genus is a source of many phytoconstituents, with alkaloids and flavonoids as the main bioactive components. Erythrina alkaloids are characterized by a unique nucleus. One hundred ninety-eight alkaloids were isolated from Erythrina plants till early 2023. Recently, an increase in the number of isolated dimeric alkaloids has been witnessed. Erythrina plants have been used in the management of different conditions as oxidative stress and diseases like cancer, inflammation, viral diseases, malaria, and diabetes, with the alkaloids showing a good potential against certain neurological disorders like anxiety, epilepsy, and Alzheimer's disease. All data on Erythrina alkaloids were collected from Google Scholar, ScienceDirect, SCOPUS, SciFinder. For compounds isolated from multiple Erythrina species, the plant source was traced only from 2008 till 2023. The reported anxiolytic, anti-convulsant, anti-Alzheimer's activities of Erythrina plant metabolites were traced from 2002 till 2023.

DOI

10.21608/aps.2023.207482.1119

Keywords

Erythrina, alkaloid, Alzheimer’s disease, anxiolytic, Anticonvulsant

Authors

First Name

Ahmed

Last Name

Salem

MiddleName

M.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo 11566, Egypt.

Email

ahmed.m.salim@pharma.asu.edu.eg

City

-

Orcid

-

First Name

Nada

Last Name

Mostafa

MiddleName

M.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo 11566, Egypt.

Email

nadamostafa@pharma.asu.edu.eg

City

Cairo

Orcid

0000-0003-1602-2725

First Name

Eman

Last Name

Al-Sayed

MiddleName

-

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo 11566, Egypt.

Email

em_alsayed@pharma.asu.edu.eg

City

-

Orcid

0000-0001-7869-2009

First Name

Abdel-Nasser

Last Name

Singab

MiddleName

B.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo 11566, Egypt. , Center for Drug Discovery Research and Development, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo 11566, Egypt.

Email

dean@pharma.asu.edu.eg

City

-

Orcid

-

Volume

7

Article Issue

1

Related Issue

40766

Issue Date

2023-06-01

Receive Date

2023-04-27

Publish Date

2023-06-01

Page Start

171

Page End

199

Print ISSN

2356-8380

Online ISSN

2356-8399

Link

https://aps.journals.ekb.eg/article_308016.html

Detail API

https://aps.journals.ekb.eg/service?article_code=308016

Order

308,016

Type

Review Article

Type Code

658

Publication Type

Journal

Publication Title

Archives of Pharmaceutical Sciences Ain Shams University

Publication Link

https://aps.journals.ekb.eg/

MainTitle

Erythrina Alkaloids: An Updated Review with Neurological Perspective.

Details

Type

Article

Created At

24 Dec 2024