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387076

Screening for allergic disorders among adults and children with kidney disease

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Allergy
Pediatrics

Abstract

Background: Patients with kidney disease may exhibit various allergic disorders and allergy mimickers. Recognition of these reactions is essential to establish correct diagnosis and initiate the proper treatment. We sought to assess the frequency of different allergic disorders among adults and children with kidney disease Methods: We conducted a cross-sectional study focusing on screening for allergic manifestations among 170 patients (130 adults and 40 pediatric) with different renal diseases. All cases were screened using an allergy questions checklist including allergy type, trigger, duration, associated symptoms, and use of anti-allergic medications. Patients were subjected to laboratory assessment including renal function tests, serum electrolytes, parathormone and complete blood picture. Results: We enrolled 55 patients with acute and 115 patients with chronic renal disease including 41 patients on regular hemodialysis. Thirty-nine percent of patients complained of one or more allergic manifestations, with the bronchial asthma most prevalent (19.4%) followed by allergic rhinitis (7.1%). In the adult group, 40% of patients had allergic diseases; 21.5% had asthma followed by allergic rhinitis (6.9%), while 9.2% had chronic kidney disease-associated pruritus (CKDaP). In the pediatric group, 37.5% had allergic diseases including asthma (12.8%), allergic rhinitis (7.5%), while 10% of patients had CKDaP. Allergic and non-allergic patients were comparable in terms of their clinicodemographic data and laboratory assessment except for higher platelet count among allergic patients (p=0.022). Urea and parathormone hormone (PTH) levels were higher among patients with CKDaP (p-value <0.05). Conclusion: Kidney diseases are associated with a complex array of allergic manifestations. Awareness of allergy disorders and differentiation from allergy mimickers would help in proper direction of the management plan, decreasing comorbidities and improving quality of life.

DOI

10.21608/ejpa.2024.306925.1072

Keywords

allergic diseases, adults, children, Kidney disease

Authors

First Name

Emad

Last Name

Elshebiny

MiddleName

Mohamed

Affiliation

Rheumatology & Immunology Division, Department of Internal Medicine, Faculty of Medicine - Menoufia University, Egypt.

Email

emadelshebini@gmail.com

City

shebin elkom

Orcid

-

First Name

Walaa

Last Name

Hashish

MiddleName

Ahmed

Affiliation

Department of internal medicine Shebin Elkom Teaching Hospital, Menoufia , Egypt

Email

walaaahmed5653@gmail.com

City

-

Orcid

-

First Name

Heba

Last Name

Abd Elsalam

MiddleName

Badawy

Affiliation

Department of pediatrics, Faculty of Medicine- Menoufia University, Egypt

Email

badwy.heba@yahoo.com

City

-

Orcid

-

First Name

Eslam

Last Name

Abd-Elaziz

MiddleName

Said

Affiliation

Internship Unit, faculty of Medicine, Menoufia University Egypt

Email

seslam518@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Essa

MiddleName

Emadeldeen

Affiliation

Internship unit Faculty of medicine Menoufia university ,Egypt

Email

mohamedemad201198@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

El- Ghorieb

MiddleName

Saber

Affiliation

Department of Internal Medicine, Nephrology unit, Faculty of Medicine- Menoufia University, Egypt

Email

ahmedelghorieb123@gmail.com

City

-

Orcid

-

Volume

22

Article Issue

2

Related Issue

50888

Issue Date

2024-10-01

Receive Date

2024-07-26

Publish Date

2024-10-01

Page Start

90

Page End

100

Print ISSN

1687-1642

Online ISSN

2314-8934

Article File

EJPA_Volume 22_Issue 2_Pages 90-100.pdf

PDF . 309.1kB

Link

https://ejpai.journals.ekb.eg/article_387076.html

Detail API

https://ejpai.journals.ekb.eg/service?article_code=387076

Order

387,076

Type

Original Article

Type Code

643

Publication Type

Journal

Publication Title

The Egyptian Journal of Pediatric Allergy and Immunology

Publication Link

https://ejpai.journals.ekb.eg/

MainTitle

Screening for allergic disorders among adults and children with kidney disease

Details

Type

Article

Created At

24 Dec 2024