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395021

Effecting of Radon Gas on Some Antioxidant and Liver Enzymes of Female Rats

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Last updated: 03 Jan 2025

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Abstract

Uranium and its daughters such as radium-226 and radon gas are harmful elements to the human body, it is considered a known carcinogen. Radon exposure can significantly affect the enzymes such as antioxidant enzymes and Liver enzymes. Liver function tests measure how well the liver performs its normal protein-making function and eliminates bilirubin. Other tests on liver function measure the enzymes released by liver cells in response to damage or disease. The present study aimed to determine the effect of radon gas (radium-226 source) on the female rats including a survey change in some antioxidant enzymes (Catalase, Glutathione, LDH, and SOD) and liver enzymes (ALT and AST).  The current study included divided the animals to five groups each group contain five animals. The first group rats were no exposed to radon gas which it is as control group. While other groups of rats (4 groups) were exposed to radon gas concentrations 588.51 Bq/m3 of 4 days, 714.62 Bq/m3 of 8 days, 756.66 Bq/m3 of 12 day, and 840.73 Bq/m3 of 16 days, respectively. The result of body weight shows no significance (P>0.05) in the body weight of rats in groups exposed to radon gas in comparison with the control group. In addition, the result of the Catalase, Glutathione, SOD, ALT and AST shows a significant decrease (P<0.05) in groups exposed to radon gas in comparison with the control group, while the LDH is significantly increased (P<0.05) in groups exposed to radon gas in compare with the control group. Therefore, it may be concluded the radon gas at high-time exposure causes effective on antioxidant and liver enzymes in female rats.

DOI

10.21608/ejhc.2024.395021

Keywords

SOD, CAT, GSH, LDH, ALT, AST female rats, and radon gas

Authors

First Name

Sajad

Last Name

A. Algazali

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Affiliation

Department of Ecology, Faculty of Science, University of Kufa, Najaf, Iraq & Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq.

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First Name

Younis

Last Name

Abdulridha Alkhafaji

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Affiliation

Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq.

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First Name

Ahmed

Last Name

T. H. Faris Al-Karkhi

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Affiliation

College of Medicine, Al-Mustaqbal University, 51001 Babylon, Iraq.

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First Name

Ammar

Last Name

Badri Younes

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-

Affiliation

Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq.

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First Name

Mahmoud

Last Name

M. Al-Mukhtar

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Affiliation

Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq.

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First Name

Mohammed

Last Name

Abdullah Jassim

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Affiliation

Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq.

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First Name

Adhraa

Last Name

Baqir Hassan

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-

Affiliation

Department of Biology, Faculty of Science, University of Kufa, Najaf, Iraq

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Orcid

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First Name

Ali

Last Name

Abid Abojassim

MiddleName

-

Affiliation

Department of Physics, Faculty of Science, University of Kufa, Najaf, Iraq

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Orcid

-

First Name

Abdulhussein

Last Name

A. Alkufi

MiddleName

-

Affiliation

Education Directorate of Najaf, Ministry of Education, Al-Najaf, Iraq

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First Name

zaid

Last Name

A. Alsaialy

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-

Affiliation

Medical Laboratory Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq

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Orcid

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First Name

Heba

Last Name

G. Abdelzaher

MiddleName

-

Affiliation

Department of Clinical pharmacy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.

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Volume

15

Article Issue

4

Related Issue

50760

Issue Date

2024-12-01

Receive Date

2024-12-04

Publish Date

2024-12-01

Page Start

978

Page End

984

Print ISSN

1687-9546

Online ISSN

3009-6766

Link

https://ejhc.journals.ekb.eg/article_395021.html

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https://ejhc.journals.ekb.eg/service?article_code=395021

Order

395,021

Type

Original Article

Type Code

631

Publication Type

Journal

Publication Title

Egyptian Journal of Health Care

Publication Link

https://ejhc.journals.ekb.eg/

MainTitle

Effecting of Radon Gas on Some Antioxidant and Liver Enzymes of Female Rats

Details

Type

Article

Created At

24 Dec 2024