Background: Context Congestive Heart Failure (CHF) is a complicated clinical condition resulting from the heart's inability to effectively pump blood to meet the body's metabolic demands.  CHF is the predominant cause of mortality and disability globally, with greater incidence in low- and middle-income nations. Self-efficacy (SE) is a crucial factor that influences a patient's capacity to control their care by enhancing patient knowledge and practice. This study aimed to assess the impact of a competency-based learning program on SE in patients with CHF. Research design: A quasi-experimental research design was utilized. The experiment was conducted in outpatient cardiac clinics at Zagazig University Hospitals. Settings: The study sample consisted of seventy adult patients, purposefully recruited from both genders. Tools: Data gathering utilized three tools: a patient interviewing assessment questionnaire, an observational checklist, and the Chronic Disease SE Scale. Results indicated that most of the investigated patients were male, with 84.2% aged between 53 and 63 years, and 62.8% presenting with comorbidities, mostly hypertension and diabetes mellitus. Statistically substantial enhancements were observed in patients' knowledge, practices, and SE following the intervention period. Conclusion: The applied learning program positively influenced SE in patients with CHF by enhancing their knowledge and behaviors. Recommendations: Consistent follow-up for all patients with CHF to assess their health status and identify problems promptly.