Background: Diabetic foot ulcers is one of the most common diabetic complications found today. These ulcers can often lead to infection, gangrene, limb amputation and even death. Studies have shown that a diabetic amputee has a 50% risk of amputation of the other lower limb during the first 2 years and a mortality rate of up to 50% during the first 3 years after a lower limb amputation. Therefore, there is an increasing need for nursing intervention in the care of diabetic patients. Design Of The Study: A descriptive study design has carried out to nurses' knowledge toward nursing care of diabetic foot ulcers at diabetic center in Merjan medical city. The study had started from October 15^th of 2023 to April 1^st of 2024. Setting Of The Study: In order to obtain more specific and precises and accurate data, the study was conducted at diabetic center in Merjan Medical City the designated site for data collection. Instrument Of The Study: Through an extensive review of relevant literature, the study instrument is constructed for the purpose of the study. It is comprised of two parts and the overall items included in these questionnaires are (20) items Sample Of The Study: A purposive sampling technique that is non – probability of (50) nurses who working in diabetic center at the time of the study period and met the studying criteria and have a prior agreement to participate who were selected (5) nurses for pilot studies and had been excluded. Data Collection: Data has been collected through the utilization of the developed questionnaire through using interview technique of all available contacts that facilitate the access to the study sample. The duration of interview approximately (10-15) minutes. The data collection process was started from December 1^st 2023 to January 1^st 2024. Conclusions: Overall assessment level of overall assessment level nurses' knowledge toward diabetic foot ulcers in present study as a general is good level. Recommendations: Establishment plans of training and development for nursing staff to increase their knowledge, awareness, and skills about the nursing care which provided the patients with diabetic foot ulcers.