Background: Infertility in women is on the rise, affecting every aspect of their lives. The impact of infertility on sexual and marital functioning is one of the most significant. Infertility's psychological effects may have a detrimental influence on marital and sexual fulfillment. One can observe an improvement in women's marital and sexual functioning by using educational models. Aim: to investigate the effectiveness of nursing counseling guided by BASNEF model on stress, anxiety, marital and sexual satisfaction among infertile women. Design: A quasi-experimental study design was used (pre and post-intervention). Setting: The study was carried out at the outpatient clinic of the Obstetrics and Gynecology Department in Sohag University Hospital. Sampling: A convenient sample of one hundred infertile women was included in the study. Tools: To gather the data, five tools were employed: a structured interview questionnaire; the perceived stress scale, the Arabic version of the Tylor anxiety scale; the female sexual function index; and ENRICH marital satisfaction index.  The results: The results of the study showed a very significant difference in the study of Infertile women's stress, anxiety, marital and sexual satisfaction pre and post-nursing counseling guided by BASNEF model implementation. Conclusion: Implementation of nursing counseling guided by BASNEF model significantly improved the Stress, Anxiety, Marital and Sexual Satisfaction among Infertile Women. Recommendation: It's suggested to use a BASNEF counseling model to improve stress, anxiety, and marital and sexual satisfaction.