Background: Intimate relationships depend heavily on sexual activity, which is an essential component of overall health. Evidence-based nursing care has emerged as a valuable approach to improve the health of patients and enhancing the standard of management. Purpose: To investigate the effect of evidence-based nursing care on the quality of sexual life among women with stress urinary incontinence. Research design: A pair of groups (which consist of a study group alongside the control group) participated in a quasi-experimental research design. Setting: Menoufia University Hospital and Shebin El-Kom Teaching Hospital's obstetrics and gynecological outpatient clinics served as the study's settings. Sample: A purposive sample of 88 women was selected. Instruments: The Incontinence Severity Index, Female Sexual Function Index, and Sexual Quality of Life-Female were used, along with a structured interview questionnaire. Results: The study's findings demonstrated that, prior to the intervention, there was no statistically significant change in the female sexual function index between the study and control groups. However, there was a statistically significant difference in the study and control groups' scores of the female sexual function index after three and six months of the intervention. Furthermore, after three and six months of the intervention, there was a statistically significant difference in the quality of sexual life scores between the study group and the control groups, compared to before the intervention. Conclusion: According to the study's findings, women with stress urinary incontinence could have better sexual experiences when they received evidence-based nursing care. Recommendations: Provide comprehensive education about stress urinary incontinence, its impact on sexual life, and available treatment options.