Background: The career maturity of the nurse interns influences their career choices and their personal career development. To enhance a person's creativity for future decisions, it is crucial to acknowledge their creative potential. The aim of this research: assessing the relation between career maturity and creativity as perceived by nurse interns Design: a descriptive, correlational study approach. Setting: Four Ain Shams University-affiliated hospitals included in the research. Subject: 115 nursing interns who enrolled for the academic year 2022-2023 served as the study's subjects. Data gathering instruments: Two instruments—the Career Maturity Inventory questionnaire and the Kaufman Domains of Creativity Scale—were used to gather the data. Results: Majority of nurse' intern had moderate level in different dimensions and total career maturity. Also, the majority of nurse' interns had moderate creativity level in different domains and total creativity level. In terms of inventiveness and professional maturity. Conclusion: According to nursing interns, there was a strong statistically significant association between overall career maturity and overall creativity. Recommendations: provision of information to nurse' intern about occupation and their requirements, decision-making process through seminars, workshops, educational programs, and other training activities. Maintaining that the educational environment encourages creative thinking, as nursing instructor, performs a crucial role in the improvement of nurse' intern creativity.