Background:Feelings of stress and agitation are hallmarks of anxiety, which can also cause changes in the body including increased blood pressure, tremors, shaking, feeling dizzy or feelings of palpitation. Nursing students are exposed to many stressors. These stressors may interfere with their personnel and practical life affecting their ability to cope with the surrounding challenges. Nursing students must possess necessary skills to cope with their environment and achieve adaptation. Resilient students are defined in terms of their capacity to deal with changes. Objectives:Toassess anxiety level and resilience level and detect the relation between anxiety and resilience among nursing students.Methods:Thisdescriptive crosssectional study was conducted incollege of nursing,Qassim University, KSA. The sociodemographic questionnaire,ResilienceScaledeveloped by Connor and Davidson, and Beck Anxiety Scale were completed by 152nursing students.The data were analysed using SPSS program.Results:About (61.8%) of the participants were diagnosed to have low anxiety levels, (23%) moderate anxiety while only (15.2%) had severe anxiety. The mean resilience score, was 68.67±14.39. There was significant negative correlation between total anxiety and resilience scores (r = -0.389 and P = 0.001*).Conclusions: Mental health issues, such as anxiety, still have a significant impact on people who are pursuing a nursing education. The association between anxiety and the stress associated with practice was significantly mediated by resilience. High-resilience nursing students had inner strengths, that enable them in overcoming difficult situations. Resilience serves as a stress-reduction tool and aids in students' recovery from mental health difficulties.Recommendations:Stress surrounding the life of nursing students so, they need more support and facilities.The four-year educational program at the nursing school should offer facilities and chances for students to practice stress management techniques, including acquiring resilience.