Background: The most often recommended medications for kids are antibiotics, although sadly many of them have the potential to cause diarrhoea that is connected with antibiotic use. An AAD is a most pediatric problem in both inpatient as well as outpatient settings. Probiotics are substances found in some meals and supplements that may help cure AAD. Because of this, the aim of present research is to: evaluate the effect of probiotic yogurt to traditional yogurt on the treatment of AAD in young patients receiving antibiotics. Design: A quasi experimental research design. Setting: The research was carried out at Minia University Hospital for Obstetrics and Paediatrics (MUHOP) and Misr El-Hora General Hospital which are associated with the Ministry of Health and Population in the paediatric medical ward and PICU.  Sample: A purposeful sample of 150 children was randomly assigned to one of three groups (probiotic yogurt, traditional yogurt, and control). Two tools were used: a structured interview questionnaire and an AAD record.  Results: The current research found that more than fifty percent of the study and control groups were males, with a mean age of two years. Furthermore, the probiotic yogurt group had the lowest mean frequency and duration of AAD, as well as the lowest percentage of AAD degree, preceded by the traditional yogurt group, and lastly the control group. Conclusion: Probiotic yogurt was useful in the treatment of AAD.  Recommendations: Parents and nurses were educated about the necessity and effectiveness of probiotic yogurt and food in the management of AAD.