Background: Myocardial infarction is a serious condition; timely treatment is important and slight delay results in severe consequences. Following acute myocardial infarction, many patients are left traumatized physically and emotionally. Assessing needs for myocardial infarction patients is very important to clarify patients' needs, meeting biopsychosocial and learning needs. Aim: This study aimed to assess the biopsychosocial and learning needs for patients with myocardial infarction. Study design: Exploratory descriptive design was used to conduct this study. Setting: This study was conducted in Coronary Care Unit at Fayoum University hospital. Subjects: Purposive sample included 120 patients in Coronary Care Unit. Tools of data collection: I. patient's assessment sheet: It included the following parts: Part (1): Patients' demographic data. Part (2): patients' medical history. II. Biopsychosocial needs, learning needs assessment tools: It included four categories (physical, psychological, social and learning needs). Results: Regarding physical needs; the present study revealed that 49.2% of patients under study had extreme/ sever physical complaints, 55.0% of them were partially dependent. Regarding psychological needs 26.7% of them had moderate depression. 20.0% of them had moderate anxiety. 20.8% of them had moderate stress. 67.5% of them were somewhat of the time had social needs. 62.5% of them had moderate learning needs. Conclusion: This study has indicated that about half of studied patients had extreme/ sever physical complaints, more than half of them were partially dependent, regarding psychological needs, around one quarter of the studied patients had moderate depression, anxiety and stress. While more than two thirds of them were somewhat of the time had social needs and two thirds of them had learning needs. Recommendations: Simple booklet written in Arabic language suggested to developed and be available for all patients with myocardial infarction. Continuous assessment of biopsychosocial and learning needs for myocardial infarction patient after discharge