Background: End Stage Renal Disease (ESRD) is one of the major health
problems worldwide. Aim of the study: Was to evaluate the effect of educational guidelines
on knowledge, practice, and dependency level for Patients with ESRD undergoing
hemodialysis. Subjects and methods: Research design: A pre/posttest quasi experimental
design was used to achieve the study aim. Setting: The study was established in
hemodialysis unit at Zagazig University Hospitals, Egypt. Subjects: Purposive sample of 60
adult patients with ESRD undergoing hemodialysis. Data collection tools: An interviewing
questionnaire for patients, patients' health care practices about special care, and Dependency
level assessment questionnaire. Results: A significant improvement was detected in patients'
knowledge and practice post educational guidelines than pre educational guidelines (p<0. 01).
Also, 20% of studied patients were dependent in performing daily living activities before
educational guidelines; meanwhile they were slightly decreased to 15% after the educational
guidelines. Conclusion: It can be concluded that, the development of educational guidelines
showed a significant effect on improvement patients' knowledge, practices, together with
modifying the dependency level. Recommendation: Carry out different related educational
guidelines and counseling sessions for patients with ESRD regarding proper intervention,
healthy lifestyle, and coping strategies.