Background: Breast cancer in women is the most common type of cancer in the world. Risk factor of breast cancer is increasing with many unhealthy lifestyle factors such as smoking, alcohol, obesity Aim of the study The study aimsto assessthe awareness of nursing studentsregarding to breast cancer at New – valley government. Research design: A descriptive research design was utilized. Setting: The study was carried out at two clinical institute of nursing at New - Valley government affiliated to ministry of health. Sample: A total of 200 students representing all scholastic years from the two clinical institute of nursing. Data collection tools: Three tools were used in this study; first tool: self-administrative questionnaire to assess nursing students' knowledge about breast cancer, second tool: Checklist to assess their practice level about breast self-examination and third tool: Likert type scale to assess their attitude. Results: this study indicated that, mean age of studied students was 19.1 ± 6.3 years, 63% & 94% of studied students were female and single, 51% of them had poor level of knowledge about breast cancer, 66% of them had positive attitude regarding to breast cancer, 32% of them were competent regarding to breast Self-Examination. Conclusions: The current study was concluded that there was highly significant positive relations between total student's knowledge about breast cancer and their total practice and attitude. Recommendations: The study recommended that provide educational programs through; Increasing nursing students' knowledge regarding breast cancers, improving nursing students' practice regarding breast cancers through, and enhancing nursing students' attitude regarding breast cancers. provide nursing students with curriculum that included BSE and it's importance. Provide sufficient opportunities for the nursing studentsfor clinical training on BSE.