Background: Getting more attention from academic institutions as well as professional organizations all around the world has made research ethics a hot topic in recent years. Public trust in scientific research and ethical standards are interdependent. Aim: The actual research aimed to investigate the impact of orientation workshop on postgraduate students' awareness about ethical issues of scientific research. Methods: A quasi-experimental research design  was carried out to accomplish the study aim by utilizing an electronic survey designed by the investigatorscontaining2 parts; participants demographics items as well as the Scientific Research Ethics Awareness Questionnaire used for gathering data through total counting as a sampling methods involving all convenient postgraduate students enrolled during the Academic year 2021/2022 in the preliminary course for master's degree at the Faculty of Nursing – Minia University, Egypt. Results of the research: Findings mentioned that most of the postgraduate nursing students exhibit an increased awareness about ethical issues of scientific research after implementing the workshop (post-test) than before its implementation (pre-test) with high statistical significance. Conclusion: Research ethics training positively effect on the development of postgraduate nursing research studies candidates' awareness about research ethical rules and regulations. Recommendations: Study findings bring attention to the significance of incorporating learning about research ethical rules and guidelines into both under and post graduate nursing curricula. Nursing faculties should emphasize the purpose and function of research ethics committees in setting institutional norms for research ethics.