Background: Cardiac rehabilitation programmes have demonstrated efficacy in the treatment of individuals afflicted with cardiovascular illness; nevertheless, only a meagre 10% of the eligible patient population partakes in such initiatives. The widespread adoption of internet connectivity and cellular telephony has presented possibilities for patient interaction and bridging geographical gaps. Aim: This study aimed to evaluate the effect of a mobile-based rehabilitation programme on quality of life among cardiac patients. Research design: The present study was designed using a quasi-experimental research approach that involved a single group receiving both pretest and posttest assessments. Setting: The study was undertaken in the cardiology inpatient ward and outpatient clinic of the Specialised Medical Hospital at Mansoura University Hospitals in Egypt. Subjects: A purposive sample of 50 patients with cardiac diseases was enrolled in this study. Tools: Data was collected using five tools: a demographic and health-relevant data questionnaire, a dietary instrument for nutritional evaluation, a hospital anxiety and depression scale, a general self-efficacy scale, and health-related quality of life measures. Results: The results indicate a statistically significant improvement in participants' quality of life after six months in comparison with basal parameters (p = 0.002). In addition, at the 6-month mark following the intervention, noteworthy enhancements were observed in the step count. Conclusion: The present study ascertained that a mobile-based rehabilitation programme was effective in improving overall quality of life among cardiac patients. Recommendation: Healthcare institutions should integrate virtual technology like mobile into cardiac rehabilitation to positively affect patients on various clinical outcomes.