Background: Children who have a ventriculoperitoneal shunt (VP shunt) have to deal with a number of difficulties, all of which have an effect on how well they can execute the daily tasks associated with self-care. Children who have ventriculoperitoneal shunts may have a variety of effects on their physical, psychological, social, and academic self-care performance. These effects may vary from child to child. Aim: The study aimed to explores Self-care performance of children with ventriculoperitoneal- shunt. Tools: Two tools were used to collect data the structured interview questionnaire and Self-care Assessment Scale. Design: A descriptive exploratory design was used. Sample: A convenient sample of eighty children with VP shunt was participated in the study. Setting: outpatient clinic of Cairo University Specialized Pediatric Hospital. Result: there was a low level of performance in children with ventriculoperitoneal- shunt recruited from. Conclusion: The current study concluded that the low level of self- care performance of children with VP shunt related to physical, psychological, social, and school performance. Recommendation:Conduct a thorough assessment of the child's self-care abilities, including physical, emotional, and social aspects and develop an individualized care plan based on the assessment findings.