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313258

Elephantiasis Nostras Verrucosa Cutis

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

Endemic medicine

Abstract

Elephantiasis nostras verrucosa cutis (ENV) is a rare presentation of chronic lymphedema which affects gravity dependant body parts - especially lower limbs. It is clinically characterised by non-pitting edema and progressive cutaneous hypertrophy leading to hyperkeratotic papulonodules which causes a verrucose or cobblestone like appearance. Differential diagnoses include lymphatic filariasis, chromoblastomycosis as well as non-infectious conditions like lipodermatosclerosis, pretibial myedema, lipidema and venous stasis dermatitis. Although the exact pathogenesis is still not known, it is believed that as the lymphatic channels are damaged and blocked, excessive protein rich fluid accumulates in the dermis and subcutaneous tissues. This leads to decreased oxygen tension leading to decreased local skin immunity. As a result, there is increased susceptibility to infections. All these ultimately leads to swelling, fibrosis and disfiguration of the area. And a vicious cycle ensues. Our case was of a 42 years normotensive, non-diabetic male diagnosed as lymphatic filariasis 10 years ago. He presented with progressive swelling of bilateral lower limbs, left more than right with multiple clustered small nodules each of few millimetres in size affecting left lower limb. He had no other comorbidities.

DOI

10.21608/aeji.2023.225647.1305

Keywords

Elephantiasis nostras verrucosa cutis, Chronic lymphedema, Diagnosis

Authors

First Name

Rupak

Last Name

Chatterjee

MiddleName

-

Affiliation

Department of Tropical Medicine, School of Tropical Medicine, Kolkata, West Bengal, India

Email

rupakchatterjee95@gmail.com

City

-

Orcid

-

First Name

Shatavisa

Last Name

Mukherjee

MiddleName

-

Affiliation

Department of Clinical & Experimental Pharmacology, School of Tropical Medicine, Kolkata, West Bengal, India

Email

shatavisa100@gmail.com

City

KOLKATA

Orcid

0000-0001-9524-1525

First Name

Netai

Last Name

Pramanik

MiddleName

-

Affiliation

Department of Tropical Medicine, School of Tropical Medicine, Kolkata, West Bengal, India

Email

drn90pramanik@gmail.com

City

-

Orcid

-

Volume

13

Article Issue

3

Related Issue

43043

Issue Date

2023-09-01

Receive Date

2023-07-28

Publish Date

2023-09-01

Page Start

212

Page End

213

Print ISSN

2090-7613

Online ISSN

2090-7184

Link

https://aeji.journals.ekb.eg/article_313258.html

Detail API

https://aeji.journals.ekb.eg/service?article_code=313258

Order

10

Type

Images in Infectious and Endemic Diseases

Type Code

624

Publication Type

Journal

Publication Title

Afro-Egyptian Journal of Infectious and Endemic Diseases

Publication Link

https://aeji.journals.ekb.eg/

MainTitle

Elephantiasis Nostras Verrucosa Cutis

Details

Type

Article

Created At

24 Dec 2024