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Correlation Between Baseline Troponin Level and The Severity of Pulmonary Hypertension 3 Months After COVID-19 Infection in Subjects without Previous Significant Cardiovascular P

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Last updated: 03 Jan 2025

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Abstract

Background: A serious medical condition linked to pulmonary hypertension (PH), right ventricular dysfunction (RVD), and cardiovascular consequences is coronavirus (Covid-19) infection. Objective: This study aimed to assess the relation between the rise of cardiac troponin at base line investigation of COVID patients and the development of pulmonary hypertension 3 months after recovery from the infection. Subjects and methods: The study was conducted as a cross-sectional descriptive study and included 104 non-critically ill patients 3 months after recovery from Covid-19 pneumonia. They were divided into 2 groups; mild cases and moderate/severe non-critically ill cases based on the WHO criteria at the time of admission. Troponin at the time of admission was measured. A full echocardiographic assessment of the right ventricle was done, and the pulmonary artery systolic pressure was calculated for every patient. Results: In COVID-19, PH is a common complication encountered after recovery, especially in moderate/severe (non-critically ill) cases. We observed increased incidence of PH in the moderate/severe group 3 months' post-recovery, significantly correlated with the initial levels of the cardiac troponin at admission (p < /em> ˂ 0.001). Conclusions: There was a statistically significant positive correlation between troponin I levels at baseline admission and the development of pulmonary hypertension (r2 = 0.696, = < 0.001) 3 months after recovery from the infection.  

DOI

10.21608/ejhm.2024.368090

Keywords

Baseline troponin level, pulmonary hypertension, Right ventricular dysfunction, COVID-19

Volume

96

Article Issue

1

Related Issue

48863

Issue Date

2024-07-01

Receive Date

2024-07-19

Publish Date

2024-07-01

Page Start

2,525

Page End

2,530

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_368090.html

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https://ejhm.journals.ekb.eg/service?article_code=368090

Order

30

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Correlation Between Baseline Troponin Level and The Severity of Pulmonary Hypertension 3 Months After COVID-19 Infection in Subjects without Previous Significant Cardiovascular P

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Type

Article

Created At

24 Dec 2024