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366546

Risk Factors of Contrast-Induced Nephropathy after Percutaneous Coronary Interventions: An Observational Study

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Last updated: 24 Dec 2024

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Abstract

Background: Contrast-induced nephropathy (CIN) refers to a temporary decline in kidney function after using iodinated contrast agents. Identifying high-risk patients and implementing suitable preventive measures are crucial for reducing CIN incidence. Objective: This study aimed to investigate risks associated with CIN after percutaneous coronary interventions (PCI). Patients and methods: This prospective observational study included 500 patients aged 18 years or older with a glomerular filtration rate (GFR) of 60 ml/min/1.73 m² or higher who underwent PCI at Al-Husain University Hospital between January 2022 and August 2023. Results: Hypertension significantly increased the risk of AKI after PCI [adjusted OR = 15.34 (4.77-60.36, p < 0.001)]. Adjustment of hemoglobin level significantly decreased the risk of AKI [adjusted OR = 0.26 (0.12-0.53, p < 0.001)] but an increased level of LDL increased the risk of AKI after PCI [adjusted OR = 1.05 (1.02-1.08, p=0.002)] and decrease of HDL level below normal significantly increased the level of AKI [adjusted OR = 1.21 (1.03-1.46, p=0.030)]. Conclusion: Hypertension, dyslipidemia, contrast volume, and impaired cardiac parameters significantly increased the risk of AKI following PCI, while higher hemoglobin levels were protective.  

DOI

10.21608/ejhm.2024.366546

Keywords

percutaneous coronary intervention, contrast-induced nephropathy, risk factors

Volume

96

Article Issue

1

Related Issue

48863

Issue Date

2024-07-01

Receive Date

2024-07-11

Publish Date

2024-07-01

Page Start

2,500

Page End

2,506

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 96_Issue 1_Pages 2500-2506.pdf

PDF . 519.6kB

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https://ejhm.journals.ekb.eg/article_366546.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=366546

Order

26

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Risk Factors of Contrast-Induced Nephropathy after Percutaneous Coronary Interventions: An Observational Study

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Article

Created At

24 Dec 2024