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366544

Early Adulthood Obesity Impact on Left and Right Ventricular Function Assessed by Speckle Tracking Echocardiography

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Last updated: 03 Jan 2025

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Abstract

Background: With the increased prevalence of obesity worldwide, even in young adults with a lack of data on its effect on cardiac function in these age groups, the need to detect the possible changes in cardiac function with different degrees of obesity has emerged. Objective: We aimed to use 2-dimensional (2D) deformation imaging to evaluate the potential changes in cardiac function in variable degrees of obesity. Patients and methods: Our study is a single-center observational study. During the study period between September 2022 and September 2023, 323 volunteers without evidence of metabolic syndrome in their first decade of adulthood (18 to 30 years of age) with a BMI more than 25 kg/m2 were evaluated at the Cardiology Department,  Faculty of Medicine, Benha University. 123 cases were excluded due to the presence of significant valvular disease (n=53), atrial fibrillation (n= 36), systolic heart failure (n= 27), and poor image quality (n=7). Finally, the study included 200 patients as follows: Overweight (n=100) and obese (n=100). Forty participants were enrolled (n=40) as a control group. Conventional and speckle-tracking echocardiography evaluated the right (RV) and the left ventricle (LV) function and global longitudinal strain (GLS). Results: No noticeable differences were detected among the groups regarding conventional functional and dimensional echocardiographic parameters. However, significant differences between the groups were noticed regarding 2D speck­le tracking of RV global longitudinal strain (GLS), RV free-wall strain, and LV GLS (p < 0.001), with worse deformation in obese subjects. Conclusion: Obesity, even in younger ages without metabolic syndrome, is hazardous to LV and RV function, represented by worse myocardial deformation. This finding could be used in risk stratification of obese young individuals.  

DOI

10.21608/ejhm.2024.366544

Keywords

Obesity, Speckle tracking echocardiography, global longitudinal strain

Volume

96

Article Issue

1

Related Issue

48863

Issue Date

2024-07-01

Receive Date

2024-07-11

Publish Date

2024-07-01

Page Start

2,487

Page End

2,493

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_366544.html

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https://ejhm.journals.ekb.eg/service?article_code=366544

Order

24

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Early Adulthood Obesity Impact on Left and Right Ventricular Function Assessed by Speckle Tracking Echocardiography

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Type

Article

Created At

24 Dec 2024