Background: Androgenetic alopecia (AGA) is the most common non-scarring hair loss disorder, primarily affecting genetically predisposed men. It is characterized by the miniaturization of hair follicles, particularly in the frontotemporal area and vertex of the scalp. AGA has been associated with an increased risk of cardiovascular diseases, insulin resistance, metabolic syndrome, diabetes mellitus, and hypertension. Genetic and hormonal factors play significant roles in its pathogenesis.
Objective: This comprehensive review aims to highlight the etiology, clinical presentation, diagnostic approaches, and current treatment modalities for androgenetic alopecia in Al-Qalyubia Governorate, emphasizing the need for awareness and understanding of this common condition.
Methods: Data were gathered by searching and reviewing Medline databases (PubMed and Medscape) for literature on androgenetic alopecia up to 2024. Inclusion criteria were studies published in English in peer-reviewed journals discussing AGA. The quality of included studies was assessed based on ethical approval, eligibility criteria, controls, information, and evaluation methods. Relevant information was extracted independently from each qualifying study using a data collection form.
Conclusion: Current treatments for AGA are focused on modulating the signs and symptoms rather than curing the condition. These treatments can slow the progression of hair loss, prevent further hair loss, and potentially stimulate partial hair regrowth. However, patient response varies, and treatments require long-term commitment. AGA has significant social and psychological impacts, necessitating comprehensive management approaches including pharmacological therapy, cosmetic camouflage, and surgical options for severe cases.