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352202

Androgen Levels in the Third Trimester of Pregnancy in Patients with Preeclampsia

Article

Last updated: 03 Jan 2025

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Abstract

Background: Although the aetiology of pre-eclampsia is not entirely known, numerous theories have been put in relation to its causes. Finding its risk factors is crucial because to its morbid course. However, because to a lack of information regarding its origin, numerous studies have been conducted on a variety of materials in an effort to identify its causes. One of these ideas focuses on the underlying endocrine changes and quantification of different androgens. Objective: This study aimed to compare between androgens level (serum total and free testosterone) in women with preeclampsia and normal ones in the 3rd trimester of pregnancy (28-40 weeks). Patients and methods: During this study, 80 pregnant women were enrolled in this study. They were divided into two groups: Group A comprised 40 pregnant women in their 3rd trimester with preeclampsia at the time of admission, whereas group B consisted of 40 healthy normotensive women in their 3rd trimester who served as control group A with matched maternal age, gestational age, and BMI. Results: Our study revealed that free and total testosterone levels were significantly higher among pre-eclamptic cases compared to healthy women with no differences regarding maternal age, gestational age and fetal sex. Conclusion: Pre-eclamptic women had greater serum androgen levels (free and total testosterones) throughout the 3rd trimester of pregnancy, this may suggest that androgens have a role in the development of pre-eclampsia.  

DOI

10.21608/ejhm.2024.352202

Keywords

androgen, Third Trimester of Pregnancy, preeclampsia

Volume

95

Article Issue

1

Related Issue

46984

Issue Date

2024-04-01

Receive Date

2024-04-28

Publish Date

2024-04-01

Page Start

1,625

Page End

1,629

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_352202.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=352202

Order

52

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Androgen Levels in the Third Trimester of Pregnancy in Patients with Preeclampsia

Details

Type

Article

Created At

24 Dec 2024