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350103

Association of Hypoalbuminemia in Preeclampsia with Maternal and Perinatal Outcomes

Article

Last updated: 03 Jan 2025

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Abstract

Background: Preeclampsia-eclampsia (PE) accounts for 18% of maternal mortality globally, with a frequency of 5–10%. Increased capillary permeability brought on by proteinuria and endothelial degradation reduces albuminemia in PE. Interstitial edema and a drop in blood volume are caused by a reduction in colloid osmotic pressure (PCO), which activates the renin-angiotensin-aldosterone pathway. Aim: To analyze and appraise the outcomes for mothers and babies in preeclampsia (PE) based on serum albumin levels. Patients and Methods: At Al Hussein University Hospital, a prospective cross-sectional study was carried out from June to December of 2023. 100 pregnant women with preeclampsia participated in the study.  The women were split into two groups: group A had mild hypoalbuminemia with an albumin value of ≤25g/L and group B had severe hypoalbuminemia. Results: There was significant difference in mild hypoalbuminemia at different times regarding serum albumin that was lower at 35 weeks than 26 weeks and 6-9 weeks and dipstick albuminuria that was higher at 35 weeks than 26 weeks and 6-9 weeks. Also, there was significant difference in severe hypoalbuminemia group at different times regarding serum albumin that was lower at 35 weeks than 26 weeks and 6-9 weeks and dipstick albuminuria that was higher at 35 weeks than 26 weeks and 6-9 weeks. Conclusion: Pregnancy should be closely monitored for severe hypoalbuminemic pre-eclampsia since it is linked to a higher risk of negative outcomes for both the mother and the newborn than mild hypoalbuminemic pre-eclampsia.  

DOI

10.21608/ejhm.2024.350103

Keywords

Hypoalbuminemia, preeclampsia, maternal

Volume

95

Article Issue

1

Related Issue

46984

Issue Date

2024-04-01

Receive Date

2024-04-14

Publish Date

2024-04-01

Page Start

1,550

Page End

1,558

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_350103.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=350103

Order

42

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Association of Hypoalbuminemia in Preeclampsia with Maternal and Perinatal Outcomes

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Type

Article

Created At

24 Dec 2024