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350102

Comparison between Transrectal Ultrasound Guided Prostatic Biopsy versus Multiparametric Magnetic Resonance Imaging with Subsequent Magnetic Resonance Imaging Prostatic Guided Ta

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Last updated: 03 Jan 2025

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Abstract

Background: Prostate cancer (PCA) is the most frequent cancer among men. In order to overcome the practical limitations of prostate specific antigen(PSA) screening, research in recent years has focused on developing more precise imaging techniques. Objectives: This study aimed to determine the function of multiparametric magnetic resonance imaging (mpMRI) as a prebiopsy imaging decreasing the number of biopsies taken and role of combination of mpMRI finding with standard transrectal ultrasound (TRUS) guided biopsy findings to improve efficacy of standard TRUS biopsy. Patients and methods: This prospective study trial was completed on 124 patients suspicious for cancer prostate as elevated total PSA > 10 ng/ml or in grey zone and free/total ratio less than 0.18 or suspicious digital rectal examination who attended to the Urology Department of Benha University Hospital. All patients underwent mpMRI then TRUS guided systematic biopsy. Further to that, TRUS guided targeted biopsy by cognitive biopsy technique from suspicious lesions in the same session for those who had positive mpMRI finding. Results: Regarding the agreement and performance characteristics between combined systematic and targeted biopsy in relation to systematic biopsy alone among patients suspected of having prostate cancer, showed moderate agreement (k=0.499), with 73.2 % sensitivity, 77.3 % specificity, 80.4 % PPV, 69.4 % NPV and 75.0 % accuracy. Conclusions: Combined TRUS guided and Targeted biopsy improved cancer detection rate in patients with PIRADs 2, 3, 4.  

DOI

10.21608/ejhm.2024.350102

Keywords

Transrectal ultrasound guided prostatic biopsy, mpMRI, Prostate Cancer

Volume

95

Article Issue

1

Related Issue

46984

Issue Date

2024-04-01

Receive Date

2024-04-14

Publish Date

2024-04-01

Page Start

1,542

Page End

1,549

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 95_Issue 1_Pages 1542-1549.pdf

PDF . 353.6kB

Link

https://ejhm.journals.ekb.eg/article_350102.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=350102

Order

41

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparison between Transrectal Ultrasound Guided Prostatic Biopsy versus Multiparametric Magnetic Resonance Imaging with Subsequent Magnetic Resonance Imaging Prostatic Guided Ta

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Type

Article

Created At

24 Dec 2024