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Microneedling as a Mode of Delivery of Topical Medications: A Comprehensive Review

Article

Last updated: 03 Jan 2025

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Abstract

Background: Microneedling has emerged as a promising technique for transdermal drug delivery, offering a minimally invasive method to enhance the permeation of topical medications. Despite its increasing application in dermatological treatments, comprehensive reviews of its mechanisms, advantages, and therapeutic uses are scarce. Objective: This review aimed to provide a comprehensive overview of microneedling as a mode of delivery for topical medications, encompassing its mechanism of action, advantages, disadvantages, and applications in cosmetic and therapeutic delivery. Methods: An extensive literature search was conducted across multiple databases, including PubMed, Scopus, and Web of Science, to identify studies related to microneedling and its applications in drug delivery. The review focused on articles published in the last two decades. Documents in languages other than English were disqualified due to lack of translation-related sources. Conclusion: Microneedling represents a versatile and effective method for transdermal drug delivery, with a wide range of applications in both cosmetic and therapeutic contexts. Ongoing research and technological advancements are expected to further enhance its efficacy and safety, solidifying its role in modern dermatological treatments.  

DOI

10.21608/ejhm.2024.350100

Keywords

Microneedling, Transdermal drug delivery, Cosmetic dermatology, Therapeutic delivery, Topical medications, Skin rejuvenation, Vaccine delivery

Volume

95

Article Issue

1

Related Issue

46984

Issue Date

2024-04-01

Receive Date

2024-04-14

Publish Date

2024-04-01

Page Start

1,532

Page End

1,535

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_350100.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=350100

Order

39

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Microneedling as a Mode of Delivery of Topical Medications: A Comprehensive Review

Details

Type

Article

Created At

24 Dec 2024