Background: Healthcare workers especially those dealing with the patient and involved in physical demanding, intense and repetitive tasks in their practice are more predisposed to work-related musculoskeletal disorders (WMSDs). These WMSDs lead to prolonged postural abnormality and pain, which negatively affect productivity and quality of life. Objectives: This study aimed to identify the correlation between thoracic kyphosis and shoulder joint position sense among healthcare workers. Patients and methods: A cross-sectional observational study include forty-five participants of both gender with thoracic kyphosis detected by screening measurements at the start. Their ages ranged from 30-49 years old and their thoracic kyphotic angle (TKA) ranged according to age into 2 groups: (Group A) their ages ranged from 30 to 39 years old and (group B) their ages ranged from 40 to 49 years old. All subjects were right-handed. A bubble inclinometer is used to measure both TKA and joint position sense (JPS) of dominant arm among healthcare workers. Results: There was a moderate correlation between thoracic kyphosis angle and shoulder flexion and abduction joint position error (JPE) at r = 0.469 & p = 0.001 and r = 0.462 & p = 0.001 respectively. Conclusion: Thoracic kyphosis directly affects shoulder joint proprioception. Therefore, dorsal spine assessment should be considered during evaluation of shoulder joint and vice versa. So better control of the symptoms and better plan of treatment for preventing the potential disabling condition.